Vitamin E Nicotinate

CAS NO.: 16676-75-8
Molecular Formula: C35H53NO3
Molecular weight: 535.813 g/mol
Appearance: Off-white,free flowing powder

COA of Vitamin E Nicotinate:
Assay: ≥96%
Melting Point: 43℃
Loss on drying: 0.12%
Total plate count: ＜10/g
Model and yeast: ＜10/g
E.coli: Negative
Salmonella: Negative
Staphy lococcus: Negative

Main Function:
1.Vitamin E Nicotinate is used for the prevention and therapy of hyperlipidemia and atherosclerosis.
2.Vitamin E Nicotinatecan directly act on blood vessel wall and restrain the cholesterin formation. It also can enhance blood circulation and slow down the skin aging process.

Application:
Used in nutritional supplements and pharmaceutical ingredients, also could be used in food supplements and nutrition products.

Description:
Vitamin E nicotinate is an ester of vitamin E and niacin (vitamin B3). Vitamin E Nicotinate can relax peripheral blood vessels, increase blood flow, reduce capillary permeability, and inhibit the synthesis of cholesterol. Large doses can lower serum cholesterol and diacylglycerol concentrations. 50% to 80% Vitamin E Nicotinate is absorbed in the intestines. Absorption requires the presence of bile salts and dietary fat, as well as normal pancreatic function. It binds to 13-lipoproteins in the blood and is stored in whole body tissues, especially in adipose tissue. The storage capacity is available for 4 years. After metabolism in the liver, excretion is done through the bile and kidney. Niacin is absorbed in the gastrointestinal tract. In the therapeutic amount of niacin, only a small amount of the original form and metabolites are excreted from the urine. When the dosage exceeds the need, most of it is excreted through the kidney. In food, tryptophan is converted to niacin by intestinal bacteria, and niacin has peripheral vasodilating effects.