Synonyms: VialoxPeptide(Pentapeptide-3);135679-88-8;Glycyl-L-prolyl-L-arginyl-L-prolyl-L-alaninamide;SCHEMBL1552455;BYWJFRMLHFQWSR-AJNGGQMLSA-N; MolPort-044-649-455; Pentapeptide-3V
CAS NO.: 135679-88-8
Molecular Formula: C21H37N9O5
Formula Weight: 495.585
Appearance: White Powder
Main Function: Anti-wrinkle & Anti-aging
1. Reduce the depth of expression wrinkles, especially in the forehead and around eyes
2. Target the wrinkle formation mechanism of expression wrinkles in a new way, offering a alternative or complement to peptides like acetyl-hexapeptide-3.
Vialox is an anti-wrinkle ingredient that is very potent. It is found in the form of a powder kit and has been proven to reduce wrinkling by 49%. It works by reducing the contraction of muscle cells. It is widely known to be similar to Botox, but is a topical cream, not an injection, making it attractive to those who do not like the idea of injections on their face.
Vialox is primarily of interest for its ability to interfere with the communication between nerves and muscles. Unlike many nicotinic acetylcholine receptor (AChR) antagonists, Vialox affects only peripheral AChRs and has no impact on central neuronal receptors when tested in animal models. This would indicate that the peptide has effects only at the neuromuscular junction, which may make it suitable not only for cosmetic applications (as a Botox alternative), but also for use in certain spastic conditions such as tension headache, migraine headache, facial spasm, etc.
Similarly to copper peptides, Matrixyl stimulates the lower layers of the skin to heal themselves, thus accelerating the healing of wounds. Cells called fibroblasts are responsible for knitting together wounds of the skin.
Vialox stimulates the "matrix" layers in the skin -- primarily collagen and fibronectin. When stimulated, the skin produces more collagen. Loss of collagen is what leads to thinning skin and the wrinkling of newly inelastic skin. Matrixyl helps to counteract this natural part of the aging process.
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