Aceclofenacum is a non-steroidal anti-inflammatory drug with marked anti-inflammatory and analgesic properties. Aceclofenacum potently inhibits the cyclooxygenase enzyme that is involved in the synthesis of prostaglandins, which are inflammatory mediators that cause pain, swelling, inflammation, and fever. It is orally administered for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Aceclofenacum works by blocking the action of a substance in the body called cyclo-oxygenase. It displays high permeability to penetrate into synovial joints wherein patients with osteoarthritis and related conditions, the loss of articular cartilage in the area causes joint pain, tenderness, stiffness, crepitus, and local inflammation. Aceclofenacum is also to be effective in other painful conditions such as dental and gynecological conditions.
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