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The early detection and rapid detection of Novel Coronavirus is not only very important for the diagnosis of patients, but also for the effective prevention of the further spread of the epidemic, especially the detection of asymptomatic or incubation period of virus carriers which plays a key role. The successful development of the detection kit will greatly improve the detection rate of Novel Coronavirus. The above products are only used for the detection of Novel Coronavirus and another coronavirus, not for treatment. The above products are only scientific research products, do not need to obtain a product registration certificate.
This assay is a one-step lateral flow chromatographic immunoassay. The test strip in the device includes 1) a conjugate pad containing SARS-CoV-2 N protein ， SARS-CoV-2 S protein, Rabbit IgG antibody, all of which are conjugated to colloidal gold, and 2) nitrocellulose membrane containing a test line (T line) and a control line (Cline). T line is coated with anti-Human IgG antibody, anti-human IgM antibody, While Cline is coated with mouse anti-rabbit IgG antibody. During the test, SARS-CoV-2 antibody and SARS-CoV-2 N or S protein labelled with colloidal gold formed antigen-antibody complexes. If the specimen does not contain SARS-CoV-2 antibody or the SARS-CoV-2 antibody level is below the lower level, the T line will not appear. The C line is coated with mouse anti-rabbit antibody, which should bind to the gold-antibody conjugate and forms a burgundy coloured line regardless of the presence of SARS-CoV-2 antibody.
Wang yuedan, a professor of immunology at Peking University's school of basic medicine, told the media that there was no good test method so that some cases have not been confirmed. Recent improvements in testing methods have made it possible to confirm an earlier accumulation of suspected cases, leading to a sharp increase in new cases over the past two days. The world health organization also said in a statement that the current rise in cases was due to increased "search and testing" efforts.
Zhong said there had been confirmed cases of human-to-human transmission and infection among medical staff. Novel Coronavirus infections are climbing the hill, but are less contagious than SARS.
In addition, the joint prevention and control mechanism of the state council held a teleconference on January 20 to make a comprehensive deployment of the prevention and control of pneumonia caused by Novel Coronavirus infection. The national health commission has set up a leading team for the response and treatment of pneumonia caused by Novel Coronavirus infection to guide local governments in the response and treatment of the epidemic. Hubei province and other localities concerned have further fulfilled their responsibilities and taken effective measures to prevent and control the epidemic.
Experts remind, at present winter-spring respiratory tract infectious disease season, the public should pay attention to indoor ventilation as well as to cold and warm, washing hands frequently, paying attention to personal hygiene, strengthening physical exercise and avoiding to the crowded place activities. If you cough or sneeze, wear a mask or cover your nose and mouth with tissues or clothing to reduce the spread of germs. If you have fever, respiratory tract infection symptom, please go to see a doctor in time to the medical establishment.
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