Natural Plant Extract Arctigenin Powder

Extraction Source: The fruit of a kind of feverfew-Arctium lappa L.
Used Part : Root
CAS No.: 7770-78-7
Molecular Weight: 372.41
Molecular Formula: C21H24O6
Test Method: UV HPLC GC
Specification: ≥95%
Solubility: Soluble in DMSO (34 mg/ml), water (sparingly), and ethanol (25 mM).
Storage:Store at -20° C
Melting Point: 219.94 °C (Predicted)
Boiling Point: 567.00 °C at 760 mmHg (Predicted)
Density: 1.23 g/cm3 (Predicted)
Pharmacological Effects:
Inhibit the excretion of total protein in urine, improve hypercholesterolemia, strongly inhibit the production of superoxide, anti-platelet aggregation activity, anti-inflammatory effect, in vitro inhibit the growth of human type leukemia cell lines hl-60 and molt-4. Inhibit hiv-1 replication.
Application:
Used for content determination, identification, pharmacological experiment and activity screening.
It has been found to act as an agonist of adiponectin receptor 1 (AdipoR1).

Natural 99% Arctigenin Powder Improves Antioxidant Status
Arctigenin is found in burdock. Arctigenin is isolated from Cnicus benedictus, Forsythia viridissima, Arctium lappa, Ipomoea cairica and others (CCD).
Arctigenin is an effective active ingredient of traditional Chinese medicine--Arctium lappa L..
In recent years, it has been proved by scholars that it has a variety of pharmacological effects, such as anti-inflammatory, immune regulation, antiviral, anti-tumor activities, as well as certain therapeutic effects on diabetic nephropathy and some neurodegenerative diseases.
The use of arctigenin has been shown to be effective in a mouse model of Japanese encephalitis.Arctigenin is a dibenzyl butyrolactone lignan agent with anti-inflammatory and antioxidant properties. Studies describe Arctigenin to potently block TNF- α production and NO secretion. MAP kinase studies show that Arctigenin effectively inhibits the activity of MAP kinases and AP-1 activation through vigorous inhibition of MKK. Additional studies report that Arctigenin acts as a potent inhibitor of PAC-1 activity. Arctigenin has also been shown to bind to kainic acid receptors and protect neurons from neurodegeneration induced by glutamate, and inhibit HIV-1 integrase. Furthermore, this compound acts as an inhibitor of IκB phosphorylation.

Main Function
1.Anti-tumor effect,Burdock seed extract arctiin have anticancer activity;
2.Can antibacterial ingredients, the main anti-staphylococcus aureus;
3.Anti-nephritis activity, it has effective treatment of acute nephritis and chronic glomerulonephritis;
4.Promote bowel movements, lower cholesterol, reduce toxins and waste accumulation in the body, prevent and treat functional constipation;
5.It is one of the best blood purifiers.
6.Can reduced blood glucose in long time, increased the amount of carbohydrate tolerance;

COA of Arctigenin
Assay(HPLC): 98%
Identification: The thin layer should be presented with the same spots in the corresponding position of the reference.
Loss On Drying: ≤5.0%
Ash: ≤5.0%
Total plate count: ＜1000CFU/gm
Yeast & mold:＜100CFU/gm
Salmonella: Negative
E.coli: Negative
Staphylococcus: Negative

Applications
1. Arctigenin powder can applied in food field, burdock root extract is regarded as good nutrition and health of high value vegetables;
2. Arctigenin powder can applied in health product field, burdock tea can eliminate toxins, nutritional supplement, adjust the balance, suitable for many people to drink;
3. Arctigenin powder can applied in pharmaceutical field, burdock root extract contains a variety of essential amino acids in higher levels, especially those with special pharmacological effects.