Mepartricin

Mepartricin

Appearance
White Powder
Product Specification
99.9%
Place of Origin
China
MOQ
1 kg
Payment Term
T/T 100% paid in advance
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Mepartricin

Grade: Pharmaceutical Grade
CAS NO.: 11121-32-7  
Molecular Formula: C60H88N2O19 
Molecular weight: 1141.359
Appearance: White Powder
Uses: antifungal, antiprotozoal
Purity: 99.9%

 

Indications: Candida albicans vaginitis and intestinal candidiasis, can also be used for vaginal or intestinal trichomoniasis. 

 

Mepartricin is a macrolide polyene compound that is useful for urethra, prostate, and bladder function. It has been studied for use in treating chronic pelvic pain syndrome and benign prostatic hyperplasia.


Mepartricin is used in studies on sterol biosynthesis and bacterial cell membranes. It may be incorporated into liposomes.


Mepartricin has inhibitory effect on trichomoniasis, and is used for Candida albicans vaginitis and intestinal candidiasis.

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Mepartricin, the methyl ester of partricin, is a new polyene antibiotic with antifungal and antiprotozoal activity. The antitrichomonas activity in vitro is comparable to that of metronidazole, the widely used drug recently demonstrated to possess mutagenic activity and thus to be used with caution in therapy. Clinical investigations have shown that mepartricin can be successfully used in the topic treatment of vaginal trichomoniasis and candidiasis. The mutagenic activity of mepartricin has been evaluated using the Ames' test and compared to that of metronidazole. No mutagenic activity was detected for mepartricin. The drug can thus be proposed as a safer and efficient alternative to metronidazole.
Mepartricin is used in studies on sterol biosynthesis and bacterial cell membranes. It may be incorporated into liposomes.
Polyene macrolide antibiotic with unknown composition. It is obtained from Streptomyces aureofaciens. It is used as an antifungal agent, an antiprotozoal agent, and in the treatment of benign prostatic hypertrophy.

It has a strong inhibitory effect on candida albicans, similar to amphotericin B, which binds to sterol structure of the outer membrane of the fungus, interferes with the normal metabolism of the fungus, destroys the permeability of the membrane, and inhibits the reproduction of the fungus. The drug has strong inhibitory activity against candida albicans. Vaginal trichomonas also has a killing effect.

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