High-Purity Methotrexate Disodium
Methotrexate Sodium is the sodium salt of methotrexate, an antimetabolite with antineoplastic and immunomodulating properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
Methotrexate binds to and inhibits the enzyme dihydrofolate reductase, resulting in inhibition of purine nucleotide and thymidylate synthesis and, subsequently, inhibition of DNA and RNA syntheses. Methotrexate also exhibits potent immunosuppressant properties.
Ecological data: This substance may be harmful to the environment and specific attention should be paid to water bodies.
Nature and stability: It will not decompose if used and stored in accordance with specifications.
|Appearance||Light yellow or dark yellow powder|
|Synonyms||Methotrexate disodium salt; 7413-34-5; Sodium methotrexate; METHOTREXATE SODIUM; MTX disodium|
|Shelf life||3 Years|
|Storage||Sealed in a cool dry environment at 0-6℃|
|Main Function||pharmaceutical intermediate|
|Application||pharma grade or research purpose|
|Place of Origin||China|
|Payment Term||T/T 100% paid in advance|
Drum, Vacuum Packed
Pharmaceutical raw materials
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