CAS No.: 5636-83-9
Molecular Formula: C20H24N2
Molecular Weight: 292.41
Appearance: White powder
Description About Dimetindene CAS 5636-83-9
Dimetindene is an antihistamine/anticholinergic. It is a first generation selective H1 antagonist. Dimetindene is an atypical first generation H1 antagonist as it only minimally passes across the blood-brain barrier. Dimetindene is also an M2 receptor antagonist.
Dimethylpyrene is used for itching, eczema, urticaria, allergic rhinitis (allergic rhinitis), bronchial asthma, etc.
Dimetindene is used orally and topically as an antipruritic. It is used topically to treat skin irritations, such as insect bites. Dimetindene is also administered orally to treat allergies, such as hay fever.
It is commonly formulated as its maleic acid salt, dimethindene maleate.
Dimetindene is a potent antipruritic antihistamine, characterized by the small size of its effective dose and its rapidity of action. Dimetindene is an antihistamine/anticholinergic that is a selective H1 antagonist. Its effect sets in after 20 to 60 minutes and lasts several hours. Dimetindene drops as well as Dimetindene syrup is particularly indicated in pediatric practice. Dimetindene is indicated as symptomatic treatment of allergic reactions: urticaria, allergies of the upper respiratory tract such as hay fever and perennial rhinitis, food, and drug allergies; pruritus of various origins, except pruritus due to cholestasis; insect bites. Dimetindene is also indicated for pruritus in eruptive skin diseases such as chicken-pox. Dimetindene can be as an adjuvant in eczema and other pruriginous dermatoses of allergic origin.
What are the side effects of Dimetindene?
Like other medicines, Dimetindene can cause some side effects. If they do occur, the side effects of Dimetindene are most likely to be minor and temporary. However, some may be serious and may require the individual to inform the doctor or visit the nearest hospital immediately.
It is pertinent to note that side effects of Dimetindene cannot be anticipated. If any side effects of Dimetindene develop or change in intensity, the doctor should be informed as soon as possible. Do concur with your doctor and follow his directions completely when you are taking Dimetindene.
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